Expression Differentiation Is Constrained to Low-Expression Proteins over Ecological Timescales
نویسندگان
چکیده
منابع مشابه
Expression Differentiation Is Constrained to Low-Expression Proteins over Ecological Timescales.
Protein expression level is one of the strongest predictors of protein sequence evolutionary rate, with high-expression protein sequences evolving at slower rates than low-expression protein sequences largely because of constraints on protein folding and function. Expression evolutionary rates also have been shown to be negatively correlated with expression level across human and mouse ortholog...
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ژورنال
عنوان ژورنال: Genetics
سال: 2015
ISSN: 1943-2631
DOI: 10.1534/genetics.115.180547